A case of solute diuresis erroneously diagnosed as lithium-induced polyuria.
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چکیده
منابع مشابه
Lithium-induced nephrogenic diabetes insipidus: in vivo and in vitro studies.
The physiological basis for the polyuria and polydipsia occurring in some manic-depressive patients treated with lithium salts was studied in vivo and in vitro. Three lithium-treated polyuric patients, in whom other causes of a concentrating defect were excluded, had abnormal urinary concentrating abilities after a standard water depreviation test. Two of these patients failed to respond to exo...
متن کاملOn the mechanism of lithium-induced diabetes insipidus in man and the rat.
The mechanism of lithium-induced diabetes insipidus was investigated in 96 patients and in a rat model. Polydipsia was reported by 40% and polyuria (more than 3 liter/day) by 12% of patients receiving lithium. Maximum concentrating ability after dehydration and vasopressin was markedly impaired in 10 polyuric patients and was reduced in 7 of 10 nonpolyuric patients studied before and during lit...
متن کاملMechanism of Lithium Carbonate Induced Hyperdipsia
used for the treatment of some psychiatric disorders (Marples, Christensen , Christensen , Ottosen and Nielsen, 1995). Many bipolar disorder patients become stabilized during the administration of lithium carbonate. Nevertheless, it produces several unwanted side effects, including polydipsia and polyuria (Penney and Hampton, 1990). At present, it is not clear the origin and mechanism of these ...
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NephSAP 2007; 6: 199–280. 6. Halperin ML, Kamel KS. Potassium. Lancet 1998; 352: 135–40. 7. Grimm PR, Sansom SC. BK channels in the kidney. Curr Opin Nephrol Hypertens 2007; 16: 430–6. 8. Oster JR, Singer I, Thatte L et al. The polyuria of solute diuresis. Arch Intern Med 1997; 157: 721–9. 9. Mittal VK, Pierce AK, Priestley JC. Use of probenecid in ticarcillin-induced hypokalemia. Clin Ther 198...
متن کاملThe Role of Nitric Oxide in the Dysregulation of the Urine Concentration Mechanism in Diabetes Mellitus
Uncontrolled diabetes mellitus results in osmotic diuresis. Diabetic patients have lowered nitric oxide (NO) which may exacerbate polyuria. We examined how lack of NO affects the transporters involved in urine concentration in diabetic animals. Diabetes was induced in rats by streptozotocin. Control and diabetic rats were given L-NAME for 3 weeks. Urine osmolality, urine output, and expression ...
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عنوان ژورنال:
- Acta psychiatrica Scandinavica
دوره 71 1 شماره
صفحات -
تاریخ انتشار 1985